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首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細(xì)胞 /Class A(Rhodopsin) /EDNRA/β-Arrestin/CHO

EDNRA/β-Arrestin/CHO

CBP71359

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I. Background

EDNRA (Endothelin Receptor Type A) is a Protein Coding gene. Diseases associated with EDNRA include Mandibulofacial Dysostosis With Alopecia and Migraine With Or Without Aura 1. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and endothelin receptor activity.

 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin+5ug/ml blasticidin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assays for EDNRA

Transducer: β-Arrestin
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. Dose response of Endothelin 1 (swine, human) in CHO-K1 EDNRA (ET1, ETA) β-Arrestin Cell Line (C17).


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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理(上海):18240630236 華東銷售經(jīng)理(上海、江蘇、安徽):15715191010 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 華北銷售經(jīng)理:18628311252 全國(guó)銷售經(jīng)理:13816461235
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