FLT3 p.G583_Y599dup Reference Standard
CBP10625
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產品描述
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| Introduction | |
| Format | Genomic DNA |
| Description | FLT3, fms related receptor tyrosine kinase 3, activates Akt, Ras, and Erk pathways to regulate differentiation, proliferation, and survival of hematopoietic progenitor cells. Activating mutations of FLT3 are common in hematologic tumors and the internal tandem duplication (ITD) mutation is commonly observed in acute myeloid leukemia . |
| Technical Data | |
| DNA Change | c.1798_1799insGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATG |
| AA Change | p.G583_Y599dup |
| Mutation type | N/A |
| Zygosity | N/A |
| Allelic Frequency | N/A |
| Transcript | N/A |
| Cosmic ID | |
| Chr position(GRCh37) | chr13:28608258-28608308 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
